Microphysiological Systems
Engineer closed-loop microphysiological platforms for real-time monitoring and precision medicine
Microphysiological systems (MPS) are in vitro models designed to replicate key features of complex biological systems in a controlled environment. These systems provide a simplified yet biologically relevant platform to study biochemical and physiological dynamics. In our lab, we leverage MPS technology to gain deeper insights into immune function and disease progression. By integrating continuous biosensing and dynamic systems modeling, we develop closed-loop control systems for immune MPS. Our goal is to create adaptive, real-time monitoring platforms that enhance our understanding of immune responses and provide a foundation for future precision medicine applications. Through this work, we aim to bridge the gap between experimental models and clinical decision-making, ultimately developing tools that could one day assist doctors in patient monitoring and treatment optimization.
Our MPS research area focuses on:
- Immune system
- MPS instrument with integrated bioanalytics
- Multi-organ MPS instrument